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Hypokalemia may developespecially with brisk diuresis when severe cirrhosis is presentduring concomitant use of corticosteroid or adrenocorticotropic hormoneACTHor after prolonged therapyInterference with adequate oral electrolyte intake will also contribute Arcoxia price in philippines to hypokalemiaHypokalemia and hypomagnesemia can provoke ventricular arrhythmias or sensitize or exaggerate the response of the heart to the toxic effects of digitalisHypokalemia may be avoided or treated by potassium supplementation or increased intake of potassium rich foods.

If you experience any of the following symptomscall your doctor immediately or get emergency medical treatment:

Before using hydrochlorothiazidetell your doctor if you have liver diseasekidney diseaseglaucomaasthma or allergiesgoutdiabetesor if you are allergic to sulfa drugs or penicillin.

Hydrochlorothiazide blocks the reabsorption of sodium and chloride ionsand it thereby increases the quantity of sodium traversing the distal tubule and the volume of water excretedA portion of the additional sodium presented to the distal tubule is exchanged there for potassium and hydrogen ionsWith continued use of hydrochlorothiazide and depletion of sodiumcompensatory mechanisms tend to increase this exchange and may produce excessive loss of potassiumhydrogen and chloride ionsHydrochlorothiazide also decreases the excretion of calcium and uric acidmay increase the excretion of iodide and may reduce glomerular filtration rateMetabolic toxicities associated with excessive electrolyte changes caused by hydrochlorothiazide have been shown to be dose-related.

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